The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Oct. 30, 2002
Applicants:

A. Paul Alivisatos, Oakland, CA (US);

Carolyn A. Larabell, Oakland, CA (US);

Wolfgang J. Parak, Dachau, DE;

Mark Le Gros, Oakland, CA (US);

Rosanne Boudreau, Berkeley, CA (US);

Inventors:

A. Paul Alivisatos, Oakland, CA (US);

Carolyn A. Larabell, Oakland, CA (US);

Wolfgang J. Parak, Dachau, DE;

Mark Le Gros, Oakland, CA (US);

Rosanne Boudreau, Berkeley, CA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); G01N 33/58 (2006.01); B82Y 15/00 (2011.01); C12M 1/00 (2006.01); C12M 1/34 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
B82Y 15/00 (2013.01); G01N 33/588 (2013.01); C12M 23/20 (2013.01); C12M 41/46 (2013.01); G01N 33/5005 (2013.01); Y10S 977/853 (2013.01);
Abstract

Methods for determining metabolic properties of living cells through the uptake of semiconductor nanocrystals by cells. Generally the methods require a layer of neutral or hydrophilic semiconductor nanocrystals and a layer of cells seeded onto a culture surface and changes in the layer of semiconductor nanocrystals are detected. The observed changes made to the layer of semiconductor nanocrystals can be correlated to such metabolic properties as metastatic potential, cell motility or migration.


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