The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 18, 2014

Filed:

Dec. 21, 2012
Applicant:

Indian Institute of Technology Bombay, Mumbai, IN;

Inventors:

Rinti Banerjee, Mumbai, IN;

Edmund Carvalho, Mumbai, IN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/14 (2006.01); A61K 47/36 (2006.01); A61K 47/22 (2006.01); A61K 9/06 (2006.01); A61K 9/51 (2006.01); A61K 45/06 (2006.01); A61K 31/355 (2006.01); A61K 31/715 (2006.01); A61K 47/32 (2006.01); A61K 9/00 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/36 (2013.01); A61K 47/22 (2013.01); A61K 9/06 (2013.01); Y10S 977/906 (2013.01); B82Y 5/00 (2013.01); A61K 9/5161 (2013.01); Y10S 977/773 (2013.01); A61K 45/06 (2013.01); A61K 31/355 (2013.01); A61K 31/715 (2013.01); A61K 47/32 (2013.01); A61K 9/0051 (2013.01);
Abstract

The present technology provides a nanoparticulate in-situ gelling vitreous substitute, which is a liquid at room temperature to aid easy administration, such as e.g. through a small needle incision, and forms a gel within the eye, which is hydrophilic in nature, similar to the natural vitreous. The vitreous substitute formulation may include a water-soluble natural or synthetic polymer and a gelling-agent which are blended together in the presence of a cross linker, to form a gel having the properties of the vitreous humor. The process of cross linking and gelation may occur in-situ. This can be achieved by dispensing to the eye, different components of the vitreous substitute in liquid state, along with the cross linking agent.


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