The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
Nov. 27, 2012
Gilead Pharmasset Llc, Foster City, CA (US);
Darryl G. Cleary, Chapel Hill, NC (US);
Charles J. Reynolds, Greenville, NC (US);
Miriam Michelle Berrey, Durham, NC (US);
Robert G. Hindes, Skillman, NJ (US);
William T. Symonds, San Francisco, CA (US);
Adrian S. Ray, Redwood City, CA (US);
Hongmei Mo, Palo Alto, CA (US);
Christy M. Hebner, Belmont, CA (US);
Reza Oliyai, Burlingame, CA (US);
Vahid Zia, San Carlos, CA (US);
Dimitrios Stefanidis, Mountain View, CA (US);
Rowchanak Pakdaman, San Carlos, CA (US);
Melissa Jean Casteel, Burlingame, CA (US);
Gilead Pharmasset LLC, Foster City, CA (US);
Abstract
Disclosed herein are a composition and unit dosage form for the treatment of hepatitis C virus (HCV) infection comprising GS-7977 and at least one pharmaceutically acceptable excipient, as well as methods for making said composition and unit dosage form. Also disclosed herein is a method of treating a subject, preferably a human, infected with hepatitis C virus, said method comprising administering to the subject for a time period an effective amount of GS-7977 and an effective amount of ribavirin. In one aspect, the method comprises administering to the subject an interferon-free treatment regimen comprising an effective amount of GS-7977 and an effective amount of ribavirin. In a particular aspect, the method is sufficient to produce an undetectable amount of HCV RNA in the subject for at least 12 weeks after the end of the time period.