The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
Jun. 24, 2010
Ventzislav B. Vassilev, Rixensart, BE;
Virginie Van Scherpenzeel Thim, Rixensart, BE;
Normand Blais, Laval, CA;
Patrick Rheault, Laval, CA;
Ventzislav B. Vassilev, Rixensart, BE;
Virginie Van Scherpenzeel Thim, Rixensart, BE;
Normand Blais, Laval, CA;
Patrick Rheault, Laval, CA;
GlaxoSmithKline Biologicals, SA, Rixensart, BE;
Abstract
The present disclosure provides immunogenic compositions that include at least two paramyxovirus F protein antigens selected from human metapnuemovirus (hMPV), paarainfluenza virus (PIV) and respiratory syncytial virus (RSV). The antigens of the disclosed compositions are recombinant F protein polypeptides, which have been modified to stabilize the trimeric prefusion conformation. Nucleic acids encoding the antigens, as well as methods for their production and use are also provided.