The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
Jun. 30, 2011
Applicants:
Isabella Caniggia, Toronto, CA;
Martin Post, Toronto, CA;
Inventors:
Isabella Caniggia, Toronto, CA;
Martin Post, Toronto, CA;
Assignee:
Mount Sinai Hospital, Toronto, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 39/00 (2006.01); G01N 33/68 (2006.01); C07K 16/18 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
G01N 33/689 (2013.01); G01N 2800/368 (2013.01); C07K 16/18 (2013.01); G01N 2800/7038 (2013.01);
Abstract
The invention relates to reagents and methods for detecting, diagnosing and screening for conditions associated with hydroxylated hypoxia inducible factor 1-α (HIF-1α). The invention also relates to novel monoclonal antibodies specific for hydroxylated HIF-1α, or binding fragments thereof, and related nucleic acids, vectors, cells and compositions, as well as methods of using the antibodies in methods of the invention.