The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
May. 01, 2012
Masanori Aikawa, Chestnut Hill, MA (US);
Daiju Fukuda, Brookline, MA (US);
Tetsuro Miyazaki, Brookline, MA (US);
Elena Aikawa, Chestnut, MA (US);
Masanori Aikawa, Chestnut Hill, MA (US);
Daiju Fukuda, Brookline, MA (US);
Tetsuro Miyazaki, Brookline, MA (US);
Elena Aikawa, Chestnut, MA (US);
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Abstract
The present invention is directed to methods of treating or preventing a metabolic disease or disorder and cardiovascular complications and other complications thereof by administering agents that inhibit the NOTCH signaling pathway. In addition, the invention encompasses methods for determining whether a patient is at increased risk for developing these conditions by determining the amount, function, or activity of NOTCH pathway components in biological samples derived from the patient or in imaging analysis.