The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2014
Filed:
Feb. 15, 2008
Ira S. Mellman, San Francisco, CA (US);
Tarek M. Fahmy, New Haven, CT (US);
William Mark Saltzman, New Haven, CT (US);
Michael J. Caplan, Woodbridge, CT (US);
Ira S. Mellman, San Francisco, CA (US);
Tarek M. Fahmy, New Haven, CT (US);
William Mark Saltzman, New Haven, CT (US);
Michael J. Caplan, Woodbridge, CT (US);
Yale University, New Haven, CT (US);
Abstract
Modular nanoparticle vaccine compositions and methods of making and using the same have been developed. Modular nanoparticle vaccine compositions comprise an antigen encapsulated in a polymeric particle and adaptor elements which modularly couple functional elements to the particle. The modular design of these vaccine compositions, which involves flexible addition and subtraction of antigen, adjuvant, immune potentiators, molecular recognition and transport mediation elements, as well as intracellular uptake mediators, allows for exquisite control over variables that are important in optimizing an effective vaccine delivery system.