Aminodihydrothiazine derivatives substituted with a cyclic group

Abstract

This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; Ris optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; Rand Rare each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R, R, Rand Rare each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.;a pharmaceutically acceptable salt or solvate thereof,which is useful for treating diseases induced by production, secretion and/or deposition of amyloid β protein.