The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

May. 19, 2010
Applicants:

Gary H. Posner, Baltimore, MD (US);

Lauren E. Woodard, Baltimore, MD (US);

David R. Levine, Baltimore, MD (US);

Deuk Kyu Moon, Baltimore, MD (US);

Bryan T. Mott, Baltimore, MD (US);

Inventors:

Gary H. Posner, Baltimore, MD (US);

Lauren E. Woodard, Baltimore, MD (US);

David R. Levine, Baltimore, MD (US);

Deuk Kyu Moon, Baltimore, MD (US);

Bryan T. Mott, Baltimore, MD (US);

Assignee:

The Johns Hopkins University, Baltimore, MD (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 321/00 (2006.01); A61K 31/335 (2006.01); C07D 493/18 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 493/18 (2013.01); C07D 519/00 (2013.01);
Abstract

Monomeric and dimeric trioxane fluoroaryl amides, 5-carbon-linked, C-10 non-acetal trioxane dimer esters; trioxane silylamides; and trioxane dimer orthoesters and methods of their use for treating subjects infected with malaria or other parasitic infectious diseases including, but not limited to, toxoplasmic infection; subjects afflicted with psychiatric conditions associated with toxoplasmic infection; and subjects afflicted with cancer.


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