The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Aug. 03, 2012
Applicants:

Sanjay Bhanot, Carlsbad, CA (US);

Kenneth W. Dobie, Del Mar, CA (US);

Xing-xian Yu, San Diego, CA (US);

Brett P. Monia, Encinitas, CA (US);

Inventors:

Sanjay Bhanot, Carlsbad, CA (US);

Kenneth W. Dobie, Del Mar, CA (US);

Xing-Xian Yu, San Diego, CA (US);

Brett P. Monia, Encinitas, CA (US);

Assignee:

Isis Pharmaceuticals, Inc., Carlsbad, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12N 15/113 (2010.01); C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1137 (2013.01); C12N 2310/14 (2013.01); C12N 2310/11 (2013.01); C07H 21/02 (2013.01);
Abstract

Compounds, compositions and methods are provided for modulating the expression of diacylglycerol acyltransferase 2. The compositions comprise oligonucleotides, targeted to nucleic acid encoding diacylglycerol acyltransferase 2. Methods of using these compounds for modulation of diacylglycerol acyltransferase 2 expression and for diagnosis and treatment of diseases and conditions associated with expression of diacylglycerol acyltransferase 2 are provided.


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