The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Jun. 08, 2012
Applicants:
Jasbir Seehra, Lexington, MA (US);
John Knopf, Carlisle, MA (US);
Ravindra Kumar, Acton, MA (US);
Erik Vogan, Medford, MA (US);
Inventors:
Jasbir Seehra, Lexington, MA (US);
John Knopf, Carlisle, MA (US);
Ravindra Kumar, Acton, MA (US);
Erik Vogan, Medford, MA (US);
Assignee:
Acceleron Pharma, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 14/715 (2006.01); C07K 14/735 (2006.01); C07K 14/525 (2006.01); C07K 16/46 (2006.01); A61K 38/19 (2006.01); A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 16/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/00 (2013.01); C07K 2319/41 (2013.01); C07K 14/70521 (2013.01); A61K 38/00 (2013.01); C07K 2319/50 (2013.01); C07K 2319/30 (2013.01); C07K 2319/02 (2013.01); C07K 2319/21 (2013.01); C07K 14/7151 (2013.01); C07K 2319/23 (2013.01); C07K 2319/91 (2013.01); C07K 2319/42 (2013.01); Y10S 530/866 (2013.01); Y10S 424/809 (2013.01);
Abstract
Provided herein are glycovariant Fc fusion proteins having increased serum half lives. Also provided are methods for increasing the serum half life of an Fc fusion protein by introducing one or more non-endogenous glycosylation sites.