The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Apr. 28, 2011
Shin-ichiro Nishimura, Sapporo, JP;
Shoichi Naito, Toyonaka, JP;
Naoki Ohyabu, Toyonaka, JP;
Tatsuya Takahashi, Toyonaka, JP;
Yoshito Numata, Toyonaka, JP;
Keiko Kawamoto, Toyonaka, JP;
Shin-Ichiro Nishimura, Sapporo, JP;
Shoichi Naito, Toyonaka, JP;
Naoki Ohyabu, Toyonaka, JP;
Tatsuya Takahashi, Toyonaka, JP;
Yoshito Numata, Toyonaka, JP;
Keiko Kawamoto, Toyonaka, JP;
Shionogi & Co., Ltd., Osaka, JP;
National University Corporation Hokkaido University, Hokkaido, JP;
Abstract
An objective of the present invention is to provide a MUC1 antibody having high specificity to cancer cells. The objective has been achieved by the present inventors who found that a cancer-specific sugar chain can be specifically recognized in MUC1 and a cancer cell expressing MUC1 having such a cancer cell specific sugar chain can be recognized. The present invention provides an antibody, an antigen-binding fragment thereof or a MUC1-binding molecule, having, for example, 40-fold specificity or more for a cancer-associated structure of MUC1 as compared to that of a normal tissue-associated structure of MUC1.