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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8883810 B1

PDFFull Text
Date of Patent:
Nov. 11, 2014

Filed:

Aug. 29, 2013

Aryl methyl benzoquinazolinone m1 receptor positive allosteric modulators

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Scott D. Kuduk, Harleysville, PA (US);

Douglas C. Beshore, Lower Gwynedd, PA (US);

Christina Ng Di Marco, Conshohocken, PA (US);

Thomas J. Greshock, Collegeville, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Sylvia A. Ayler

John C. Todaro

Primary Examiner:

Noble Jarrell

Assistant Examiner:

John S Kenyon

Int. Cl.
CPC ...
A61K 31/513 (2006.01); C07D 239/72 (2006.01); C07D 409/14 (2006.01); C07D 405/14 (2006.01); C07D 471/04 (2006.01); C07D 239/88 (2006.01); C07D 401/04 (2006.01); C07D 401/14 (2006.01); C07D 401/06 (2006.01); C07D 519/00 (2006.01); C07D 403/04 (2006.01); C07D 239/70 (2006.01);
U.S. Cl.
CPC ...
C07D 239/70 (2013.01); C07D 409/14 (2013.01); C07D 405/14 (2013.01); C07D 471/04 (2013.01); C07D 239/88 (2013.01); C07D 401/04 (2013.01); C07D 401/14 (2013.01); C07D 401/06 (2013.01); C07D 519/00 (2013.01); C07D 403/04 (2013.01);
Abstract

The present invention is directed to benzoquinazolinone compounds of formula (I) which are M1 receptor positive allosteric modulators and that are useful in the treatment of diseases in which the M1 receptor is involved, such as Alzheimer's disease, schizophrenia, pain or sleep disorders. The invention is also directed to pharmaceutical compositions comprising the compounds, and to the use of the compounds and compositions in the treatment of diseases mediated by the M1 receptor.

Find Patent Forward Citations

Kuduk, Scott. (2014). Aryl methyl benzoquinazolinone m1 receptor positive allosteric modulators (U.S. Patent No. 8883810). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8883810

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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