The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Jul. 30, 2008
Jong Bae Park, Seoul, KR;
Seung Hoon Lee, Seoul, KR;
Hee Jin Kwak, Goyang-si, KR;
Tae Hoon Kim, Seoul, KR;
Heon Yoo, Seoul, KR;
Donghee Lee, Goyang-si, KR;
Eun Kyoung Park, Goyang-si, KR;
Hea Jin Kim, Goyang-si, KR;
Jong Bae Park, Seoul, KR;
Seung Hoon Lee, Seoul, KR;
Hee Jin Kwak, Goyang-si, KR;
Tae Hoon Kim, Seoul, KR;
Heon Yoo, Seoul, KR;
Donghee Lee, Goyang-si, KR;
Eun Kyoung Park, Goyang-si, KR;
Hea Jin Kim, Goyang-si, KR;
National Cancer Center, Goyang-si, KR;
Abstract
Disclosed is a radiation sensitivity-enhancing composition in which a microRNA-21 inhibitor acts as an active ingredient. The microRNA-21 inhibitor is an antisense nucleic acid molecule binding complementarily to microRNA-21. The composition can be administered to a patient in conjunction with irradiation. The inhibitor can act as a radiosensitizer, enhancing the therapeutic effect of such irradiation on cancer high in microRNA-21 expression level, particularly, glioma.