The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Nov. 24, 2010
Applicants:
Pui-kai LI, Galloway, OH (US);
Chenglong LI, Dublin, OH (US);
Jiayuh Lin, Dublin, OH (US);
Inventors:
Assignees:
The Ohio State University, Columbus, OH (US);
Nationwide Children's Hospital, Inc., Columbus, OH (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/704 (2006.01); A61K 31/7068 (2006.01); A61P 35/00 (2006.01); C07C 303/38 (2006.01); C12N 5/00 (2006.01); C07C 311/29 (2006.01);
U.S. Cl.
CPC ...
C07C 311/29 (2013.01);
Abstract
The present invention provides small molecules useful to affect cancer cells, along with related methods. The present compounds, formulations, kits and methods are useful for a variety of research, diagnostic and therapeutic purposes. STAT3 inhibitors, particularly LLL12, are disclosed. The STAT3 inhibitors are useful to treat breast cancer in general and breast cancer initiating cells in particular.