The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

May. 22, 2007
Applicants:

Moriya Tsuji, New York, NY (US);

Guangwu Chen, Flushing, NY (US);

Richard W. Franck, Riverside, CT (US);

Guangli Yang, Forest Hills, NY (US);

Inventors:

Moriya Tsuji, New York, NY (US);

Guangwu Chen, Flushing, NY (US);

Richard W. Franck, Riverside, CT (US);

Guangli Yang, Forest Hills, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 39/21 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01); A61K 39/38 (2006.01); A61K 39/29 (2006.01); C07H 13/06 (2006.01); A61K 31/7004 (2006.01); A61K 31/7042 (2006.01); A61K 31/7028 (2006.01); C07H 7/00 (2006.01); C07H 15/06 (2006.01);
U.S. Cl.
CPC ...
C07H 13/06 (2013.01); A61K 31/7004 (2013.01); A61K 31/7042 (2013.01); A61K 31/7028 (2013.01); C07H 7/00 (2013.01); C07H 15/06 (2013.01);
Abstract

The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants.


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