The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Mar. 26, 2013
Applicant:

Calpis Co., Ltd., Tokyo, JP;

Inventors:

Mari Takahashi, Shibuya-ku, JP;

Naoyuki Yamamoto, Sagamihara, JP;

Kazuhisa Yamada, Shibuya-ku, JP;

Toshirou Iketani, Akiruno, JP;

Assignee:

CALPIS Co., Ltd, Tokyo, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/06 (2006.01); A61K 38/01 (2006.01);
U.S. Cl.
CPC ...
A61K 38/018 (2013.01); A61K 38/06 (2013.01);
Abstract

An agent for reducing risk in onset of diseases ascribable to non-dipping circadian profile of blood pressure is provided. This agent is capable of effectively lowering SBP from night to early morning in individuals with non-dipping circadian profile of blood pressure, in particular, normal individuals with normal SBP and DBP among them, and is thus capable of reducing risk in onset, particularly likely in the morning, of diseases caused by circadian variation of blood pressure. The agent is intended for administration to such subjects, and contains a hydrolysate or a concentrate thereof, containing Val-Pro-Pro and Ile-Pro-Pro and obtained by hydrolysis of animal milk protein.


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