The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Mar. 04, 2008
Applicant:
Robert Patrick Doyle, Syracuse, NY (US);
Inventor:
Robert Patrick Doyle, Syracuse, NY (US);
Assignee:
Syracuse University, Syracuse, NY (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/28 (2006.01); A61K 38/02 (2006.01); A61K 38/16 (2006.01); A61P 3/10 (2006.01); A61K 47/48 (2006.01); A61K 38/26 (2006.01); A61K 38/22 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/28 (2013.01); A61K 47/48107 (2013.01); A61K 38/26 (2013.01); A61K 38/22 (2013.01); A61K 38/1709 (2013.01); A61K 38/2271 (2013.01);
Abstract
Compositions containing a therapeutic peptide covalently linked to Vitamin Bat the 5'-hydroxyl group of the ribose moiety of α-ligand are described. The length of the linkage is optimized so that the biological activity of both the Vitamin Band the therapeutic peptide is maintained. Therapeutic peptide includes insulin, PYY, NPY and GLP-1. Attachment to Vitamin Bprovides uptake of the therapeutic peptide from the digestive tract and longer residence time.