The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Nov. 25, 2009
Applicants:

Brigitte Krenn, Vienna, AT;

Markus Wolschek, Vienna, AT;

Julia Romanova, Vienna, AT;

Andrej Egorov, Vienna, AT;

Sabine Nakowitsch, Vienna, AT;

Inventors:

Brigitte Krenn, Vienna, AT;

Markus Wolschek, Vienna, AT;

Julia Romanova, Vienna, AT;

Andrej Egorov, Vienna, AT;

Sabine Nakowitsch, Vienna, AT;

Assignee:

Baxter Healthcare SA, Glattpark (Opfikon), CH;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C12N 7/00 (2006.01); C12N 7/01 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/145 (2013.01); A61K 2039/5254 (2013.01); C12N 2760/16134 (2013.01);
Abstract

The present invention provides a method for producing pH-stable enveloped viruses wherein said viruses are used for infection of host cells under low pH conditions and for incubation with cell culture cells under conditions of low pH, as well as influenza viruses obtainable by this method which exhibit a high growth rate in cell culture, increased pH and temperature stability and which have human receptor specificity.


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