The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Feb. 19, 2010
Applicants:
Qiyong Peter Liu, Newton, MA (US);
Henrik Clausen, Holte, DK;
Inventors:
Qiyong Peter Liu, Newton, MA (US);
Henrik Clausen, Holte, DK;
Assignee:
Beverly SPV1, LLC, Wilmington, DE (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/34 (2006.01); C12N 9/40 (2006.01); C12P 21/00 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C12Y 302/01022 (2013.01); C12N 9/2465 (2013.01);
Abstract
This invention relates to novel α-galactosidases for the enzymatic removal of the immunodominant monosaccharides on blood products and tissues. Specifically this invention provides a novel family of α3 glycosidases, used for the enzymatic removal of type B antigens from blood group B and AB reactive blood products, and the Galili antigen from non-human animal tissues, thereby converting these to non-immunogenic cells and tissues suitable for transplantation.