Triprenyl phenol compound, process for production of triprenyl phenol compound, and thrombolysis enhancer

Abstract

A triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), Rrepresents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; Rin the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH)Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein Rrepresents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.