The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Jan. 04, 2012
Applicants:

Keiji Hasumi, Inagi, JP;

Yoshikazu Kitano, Fuchu, JP;

Hideo Ohishi, Sayama, JP;

Haruki Koide, Hachioji, JP;

Keiko Hasegawa, Zama, JP;

Ritsuko Narasaki, Fuchu, JP;

Inventors:

Keiji Hasumi, Inagi, JP;

Yoshikazu Kitano, Fuchu, JP;

Hideo Ohishi, Sayama, JP;

Haruki Koide, Hachioji, JP;

Keiko Hasegawa, Zama, JP;

Ritsuko Narasaki, Fuchu, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 491/052 (2006.01); C12P 17/18 (2006.01);
U.S. Cl.
CPC ...
C07D 491/052 (2013.01); C12P 17/18 (2013.01);
Abstract

A triprenyl phenol compound represented by the following formula (II) and (III) and having a thrombolysis-enhancing activity, and an efficient method for producing the triprenyl phenol compound. In formula (II) and (III), Rrepresents an aromatic group having as a substituent or as a part of a substituent at least one member selected from the group consisting of a carboxyl group, a hydroxyl group, a sulfonic acid group and a secondary amino group, or an aromatic group which comprises a secondary amino group and may comprise nitrogen; Rin the general formula (III) represents an aromatic amino acid residue represented by the general formula (III-1) below; X represents —CHY—(CH)Z; and Y and Z are respectively —H or —OH or together form a single bond: (III-1) wherein Rrepresents a hydroxyl group which may be present or absent; and n represents an integer of 0 or 1.


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