The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Sep. 11, 2013
Gen-probe Incorporated, San Diego, CA (US);
Kelly G. Ammann, Boulder, CO (US);
Ralph E. Burns, Boulder, CO (US);
Ernest V. Hansberry, Blacksburg, VA (US);
Glenn A. Horner, Boulder, CO (US);
Cheryl A. Jakub, Bowling Green, KY (US);
John E. Kling, Loveland, CO (US);
Donald J. Nieglos, San Miguel de Allende, MX;
Robert E. Schneider, Erie, CO (US);
Robert J. Smith, Louisville, CO (US);
Gen-Probe Incorporated, San Diego, CA (US);
Abstract
An automated method for detecting the presence of a nucleic acid in a sample, where the method is performed within a housing of a self-contained, stand-alone analyzer. The method includes purifying the nucleic acid after it has been immobilized on a magnetically-responsive solid support. A pipette of the analyzer is used to form a reaction mixture comprising the purified nucleic acid and all reagents required to perform a nucleic acid amplification. Amplification products are synthesized that include a nucleotide sequence contained in the nucleic acid or the complement of the nucleic acid. The amplification products are exposed to a probe in a mixture, where the probe forms a hybrid with one of the amplification products. The formation of the hybrid in the mixture provides an indication of the presence of the nucleic acid in the sample.