The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Jul. 29, 2010
Applicants:

Olivier Fabrega, Newcastle upon Tyne, GB;

Arthur James, Cumbria, GB;

Sylvain Orenga, Neuville sur Ain, FR;

John Perry, Newcastle Upon Tyne, GB;

Vindhya Salwatura, Newcastle Upon Tyne, GB;

Stephen Stanforth, Northumberland, GB;

Inventors:

Olivier Fabrega, Newcastle upon Tyne, GB;

Arthur James, Cumbria, GB;

Sylvain Orenga, Neuville sur Ain, FR;

John Perry, Newcastle Upon Tyne, GB;

Vindhya Salwatura, Newcastle Upon Tyne, GB;

Stephen Stanforth, Northumberland, GB;

Assignee:

bioMérieux S.A., Marcy l'Etoile, unknown;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/26 (2006.01); C12Q 1/04 (2006.01); C07D 263/56 (2006.01); C07D 209/20 (2006.01); C07D 277/62 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/26 (2013.01); C12Q 1/04 (2013.01);
Abstract

The invention relates to the use of a compound having formula (I) as an enzymatic substrate for the detection of a nitroreductase activity, wherein: W, W, Wand Ware independently H, Br, Cl, F, I, alkyl, alkoxy, thiomethyl, perfluoroalkyl, nitro, cyano, carboxyl (including the esters or amides thereof) or any combination of same; n=0, 1 or 2; X is NR, CZZ, S or O, R being H, alkyl, aralkyl, aryl, alkanoic or alkylsulphonic, Zand Zbeing an alkyl; Y is N or NR, R being alkyl, aralkyl, aryl, alkanoic or alkylsulphonic; Z, Z, Zand Zare independently H, Br, Cl, F, I, alkyl, aryl, alkoxy, perfluoroalkyl, nitro, cyano, carboxyl, sulphonyl, including the sulphonyl or carboxyl amides or esters thereof, and the salts of same.


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