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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8883209 B1

PDFFull Text
Expired
Date of Patent:
Nov. 11, 2014

Filed:

May. 25, 2010

Pharmaceutical solid dispersions

Applicants:

Walter C. Babcock, Bend, OR (US);

Dwayne T. Friesen, Bend, OR (US);

James A. S. Nightingale, Bend, OR (US);

Ravi M. Shanker, Groton, CT (US);

Inventors:

Walter C. Babcock, Bend, OR (US);

Dwayne T. Friesen, Bend, OR (US);

James A. S. Nightingale, Bend, OR (US);

Ravi M. Shanker, Groton, CT (US);

Assignee:

Bend Research, Inc., Bend, OR (US);

Attorney:

Klarquist, Sparkman, LLP

Primary Examiner:

Jake Vu

Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 9/16 (2006.01); A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1635 (2013.01); A61K 9/1652 (2013.01); A61K 9/146 (2013.01);
Abstract

A composition comprises a solid dispersion comprising a low-solubility drug and at least one polymer. At least a major portion of the drug in the dispersion is amorphous. The polymer has a glass transition temperature of at least 100° C. measured at a relative humidity of fifty percent. Another aspect of the invention comprises the same composition except that the dispersion has a glass transition temperature of at least 50° C. at a relative humidity of fifty percent. In another aspect of the invention, a composition comprises a solid dispersion comprising a low-solubility drug and a stabilizing polymer. At least a major portion of the drug in the dispersion is amorphous. The composition also includes a concentration-enhancing polymer that increases the concentration of the drug in a use environment. The stabilizing polymer has a glass transition temperature that is greater than the glass transition temperature of the concentration-enhancing polymer at a relative humidity of 50%.

Find Patent Forward Citations

Babcock, Walter. (2014). Pharmaceutical solid dispersions (U.S. Patent No. 8883209). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8883209

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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