The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Apr. 08, 2010
Applicants:

Joseph Schmidt Mcgonigle, Saint Paul, MN (US);

Joram Slager, St. Louis Park, MN (US);

Inventors:

Joseph Schmidt McGonigle, Saint Paul, MN (US);

Joram Slager, St. Louis Park, MN (US);

Assignee:

SurModics, Inc., Eden Prairie, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/48 (2006.01); A61K 9/50 (2006.01); A61L 17/00 (2006.01); A61L 29/12 (2006.01); C12N 15/89 (2006.01); A61K 9/16 (2006.01); A61K 48/00 (2006.01); A61L 31/12 (2006.01); A61L 17/12 (2006.01); A61L 27/54 (2006.01); A61L 31/16 (2006.01); A61L 29/14 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 9/1641 (2013.01); A61L 27/48 (2013.01); A61K 9/5084 (2013.01); A61L 17/005 (2013.01); A61L 29/126 (2013.01); A61L 2300/258 (2013.01); C12N 15/89 (2013.01); A61K 9/0024 (2013.01); A61K 9/1647 (2013.01); A61K 48/0041 (2013.01); A61L 31/129 (2013.01); A61L 2300/62 (2013.01); A61L 17/12 (2013.01); A61L 27/54 (2013.01); A61L 31/16 (2013.01); A61L 29/148 (2013.01);
Abstract

Embodiments of the invention include devices and methods for the release of nucleic acid complexes. In an embodiment the invention includes a nucleic acid delivery particle. The delivery particle can include a polymeric matrix including a polyethyleneglycol containing copolymer and a nucleic acid complex disposed within the polymeric matrix. The nucleic acid complex can include a nucleic acid and a carrier agent. In an embodiment the invention includes a medical device including a first polymeric matrix comprising a first polymer and a plurality of nucleic acid delivery particles disposed within the first polymeric matrix. The medical device can be configured to release the nucleic acid complex when the medical device is implanted within a subject. Other embodiments are included herein.


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