The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Apr. 26, 2010
Applicant:
Thomas W. I. Leonard, Wilmington, NC (US);
Inventor:
Thomas W. I. Leonard, Wilmington, NC (US);
Assignee:
Merrion Research III Limited, , IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/64 (2006.01); A61K 9/20 (2006.01); A61K 9/24 (2006.01); A61K 31/675 (2006.01); A61K 31/66 (2006.01); A61K 31/19 (2006.01); A61K 9/00 (2006.01); A61K 9/16 (2006.01); A61K 9/28 (2006.01); A61K 31/20 (2006.01); A61K 31/663 (2006.01); A61K 47/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/19 (2013.01); A61K 9/0053 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/2013 (2013.01); A61K 9/2018 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2846 (2013.01); A61K 31/20 (2013.01); A61K 31/663 (2013.01); A61K 31/675 (2013.01); A61K 47/12 (2013.01);
Abstract
The invention relates to a pharmaceutical composition and oral dosage forms comprising a bisphosphonate in combination with an enhancer to enhance intestinal delivery of the bisphosphonate to the underlying circulation. Preferably, the enhancer is a medium chain fatty acid or a medium chain fatty acid derivative having a carbon chain length of from 6 to 20 carbon atoms, and the solid oral dosage form is a controlled release dosage form such as a delayed release dosage form.