The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Jul. 11, 2013
Sutter West Bay Hospital, San Francisco, CA (US);
Keelung Hong, San Francisco, CA (US);
Wei Wen Zheng, Las Vegas, NV (US);
Daryl C. Drummond, Concord, CA (US);
Dmitri B. Kirpotin, San Francisco, CA (US);
Mark Eamon Hayes, San Francisco, CA (US);
Sutter West Bay Hospitals, San Francisco, CA (US);
Abstract
Provided herein is a process for preparing a microparticulate complex of a particle-forming component ('PFC') and a nucleic acid-like component ('NAC') in a monophasic composition comprising water and a water-miscible organic solvent. Also provided is a microparticulate complex that comprises a particle-forming component complexed to a nucleic acid-like component, and a composition comprising water and the microparticulate complex. Further provided is a method of delivery of a nucleic acid-like component to a cell or to a patient by contacting the cell with or administering to the patient a composition comprising water and the microparticulate complex described herein. Still further, a charge-changing composition represented by the formula A-X—B is provided.