The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Jan. 20, 2009
Applicants:

Ronald Stewart Hill, Greenville, NC (US);

Richard Chris Klann, Washington, NC (US);

Francis V. Lamberti, Greenville, NC (US);

Inventors:

Ronald Stewart Hill, Greenville, NC (US);

Richard Chris Klann, Washington, NC (US);

Francis V. Lamberti, Greenville, NC (US);

Assignee:

Pioneer Surgical Technology, Inc., Marquette, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/39 (2006.01); A61L 27/26 (2006.01); A61K 38/18 (2006.01); A61L 26/00 (2006.01); A61K 38/01 (2006.01); A61L 27/48 (2006.01); A61L 27/52 (2006.01); A61K 35/32 (2006.01);
U.S. Cl.
CPC ...
A61L 27/52 (2013.01); A61L 27/26 (2013.01); A61K 38/1875 (2013.01); A61L 26/0052 (2013.01); A61L 26/008 (2013.01); A61L 2430/10 (2013.01); A61K 38/014 (2013.01); A61L 27/48 (2013.01); A61L 26/0057 (2013.01); A61K 35/32 (2013.01);
Abstract

Connective tissue regenerative compositions and methods of repairing and regenerating connective tissue using such compositions are provided. The compositions generally comprise a bioactive hydrogel matrix comprising a polypeptide, such as gelatin, and a long chain carbohydrate, such as dextran. The hydrogel matrix may further include polar amino acids, as well as additional beneficial additives. Advantageously, the compositions include further components, such as osteoinductive or osteoconductive materials, medicaments, stem or progenitor cells, and three-dimensional structural frameworks. The compositions are useful for regenerating connective tissue, and can be administered to an area having injury to, or a loss of, connective tissue, such as bone, cartilage, tendon, and ligament.


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