The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Aug. 23, 2010
Kazuyoshi Kaminaka, Kikuchi, JP;
Chikateru Nozaki, Kikuchi, JP;
Junichi Matsuda, Kikuchi, JP;
Kiyoto Nishiyama, Kikuchi, JP;
Kazuyoshi Kaminaka, Kikuchi, JP;
Chikateru Nozaki, Kikuchi, JP;
Junichi Matsuda, Kikuchi, JP;
Kiyoto Nishiyama, Kikuchi, JP;
The Chemo-Sero-Therapeutic Research Institute, Kumamoto-shi, JP;
Abstract
A modified peptide derived from matrix protein 2 (hereinafter also referred to as 'M2'), one of surface layer proteins of influenza virus, and a method for utilization of the modified peptide are provided. A peptide (hereinafter also referred to as 'M2eC peptide') that is made up by inserting cysteine residue(s) into a peptide (hereinafter also referred to as “M2e”) consisting of 23 amino acid residues of from positions No. 2 to No. 24 of M2 in influenza virus type A, a fusion protein consisting of said modified peptide and a polypeptide, an influenza vaccine comprising said modified peptide or said fusion protein as an active ingredient, a device which can be delivered into the body comprising said influenza vaccine, a nucleic acid fragment consisting of a nucleotide sequence encoding the amino acid sequence of said modified peptide or said fusion protein, an expression vector in which said nucleic acid fragment is incorporated, a host in which said expression vector is introduced, and an antibody that has a protective effect against influenza virus.