The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Feb. 26, 2010
Applicant:
Xiaoqing Qiu, Chengdu, CN;
Inventor:
Xiaoqing Qiu, Chengdu, CN;
Assignee:
Protein Design Lab, Ltd., Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/00 (2006.01); A61K 39/395 (2006.01); C07K 16/08 (2006.01); C07K 14/245 (2006.01); C07K 19/00 (2006.01); C07K 14/005 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/085 (2013.01); C07K 14/245 (2013.01); C07K 19/00 (2013.01); C07K 14/005 (2013.01); A61K 2039/505 (2013.01); C07K 2319/30 (2013.01); C12N 2710/16222 (2013.01);
Abstract
The present invention provides a fusion polypeptide against EB virus-induced tumor, which comprises an antibody or a mimetic antibody against EB virus and an ion channel forming colicin selected form E1, Ia, Ib, A, B, N and their mutants. The present invention also provides a colicin Ia mutant, which comprises mutations of G11A, H22G, A26G, V31L, and H40D. The present invention also provides a gene, vector, preparation method and use of the fusion polypeptide, and provides a gene and use of the mutant.