The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2014

Filed:

Apr. 25, 2013
Applicants:

Venkat R. Thalladi, Foster City, CA (US);

Jerry Nzerem, South San Francisco, CA (US);

Xiaojun Huang, Sunnyvale, CA (US);

Weijiang Zhang, Concord, CA (US);

Inventors:

Venkat R. Thalladi, Foster City, CA (US);

Jerry Nzerem, South San Francisco, CA (US);

Xiaojun Huang, Sunnyvale, CA (US);

Weijiang Zhang, Concord, CA (US);

Assignee:

Theravance Biopharma R&D IP, LLC, South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 45/06 (2006.01); A61K 31/496 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/14 (2013.01); A61K 45/06 (2013.01); A61K 31/496 (2013.01);
Abstract

The invention provides crystalline solid forms of (((S)-1-{(S)-2-[4-(4'-{[6-((2R,5S)-2,5-dimethyl-4-methylcarbamoyl-piperazin-1-yl)-pyridine-3-carbonyl]-amino}-2′-trifluoromethoxy-biphenyl-4-yl)-1H-imidazol-2-yl]-pyrrolidine-1-carbonyl}-2-methyl-propyl)-carbamic acid methyl ester. The invention also provides pharmaceutical compositions comprising such crystalline solid forms, methods of using such crystalline solid forms to treat hepatitis C virus infection, and processes useful for preparing such crystalline solid forms.


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