The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 11, 2014
Filed:
Sep. 14, 2012
D. Marshall Porterfield, West Lafayette, IN (US);
Tae-gon Cha, West Lafayette, IN (US);
Jong Hyun Choi, West Lafayette, IN (US);
Jonathan C. Claussen, Lafayette, IN (US);
Alfred R. Diggs, Chicago, IL (US);
Jin Shi, San Diego, CA (US);
D. Marshall Porterfield, West Lafayette, IN (US);
Tae-Gon Cha, West Lafayette, IN (US);
Jong Hyun Choi, West Lafayette, IN (US);
Jonathan C. Claussen, Lafayette, IN (US);
Alfred R. Diggs, Chicago, IL (US);
Jin Shi, San Diego, CA (US);
Purdue Research Foundation, West Lafayette, IN (US);
Abstract
Glucose and ATP biosensors have important applications in diagnostics and research. Combining single-walled carbon nanotubes (SWCNTs) with Pt nanoparticles can significantly enhance the performance of electrochemical biosensors. This disclosure illustrates the use of single-stranded DNA (ssDNA) to modify SWCNTs to increase SWCNT solubility in water. Multiple embodiments with this configuration allows for exploration of new schemes of combining ssDNASWCNT and Pt black in aqueous media systems. These embodiments resulted in a nanocomposite with enhanced biosensor performance. The ssDNA-SWCNT/Pt black nanocomposite constructed by a layered scheme proved most effective in terms of biosensor activity. The key feature of this structure and method of use is the exploitation of ssDNASWCNTs as molecular templates for Pt black electrodeposition. Glucose and ATP microbiosensors fabricated utilizing this structure and method of use exhibited high sensitivity, wide linear range and low limit of detection.