The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Jan. 15, 2010
Liming Shao, Lincoln, MA (US);
Fengjiang Wang, Northborough, MA (US);
Scott Christopher Malcolm, Southborough, MA (US);
Michael Charles Hewitt, Somerville, MA (US);
Larry R. Bush, Worcester, MA (US);
Jianguo MA, Natick, MA (US);
Mark A. Varney, Laguna Niguel, CA (US);
Una Campbell, Marlborough, MA (US);
Sharon Rae Engel, Hudson, MA (US);
Larry Wendell Hardy, Sturbridge, MA (US);
Patrick Koch, Marlborough, MA (US);
John E. Campbell, Cambridge, MA (US);
Liming Shao, Lincoln, MA (US);
Fengjiang Wang, Northborough, MA (US);
Scott Christopher Malcolm, Southborough, MA (US);
Michael Charles Hewitt, Somerville, MA (US);
Larry R. Bush, Worcester, MA (US);
Jianguo Ma, Natick, MA (US);
Mark A. Varney, Laguna Niguel, CA (US);
Una Campbell, Marlborough, MA (US);
Sharon Rae Engel, Hudson, MA (US);
Larry Wendell Hardy, Sturbridge, MA (US);
Patrick Koch, Marlborough, MA (US);
John E. Campbell, Cambridge, MA (US);
Sunovion Pharmaceuticals Inc., Marlborough, MA (US);
Abstract
The invention relates to novel cyclohexylamine derivatives and their use in the treatment and/or prevention of central nervous system (CNS) disorders, such as depression, anxiety, schizophrenia and sleep disorder as well as methods for their synthesis. The invention also relates to pharmaceutical compositions containing the compounds of the invention, as well as methods of inhibiting reuptake of endogenous monoamines, such as dopamine, serotonin and norepinephrine from the synaptic cleft and methods of modulating one or more monoamine transporter.