The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Jan. 08, 2009
Applicants:

Craig Zimmerman, Topsfield, MA (US);

John W. Babich, Cambridge, MA (US);

John Joyal, Melrose, MA (US);

Genliang LU, Winchester, MA (US);

Kevin P. Maresca, Tewksbury, MA (US);

Chris Barone, Roxbury Crossing, MA (US);

Inventors:

Craig Zimmerman, Topsfield, MA (US);

John W. Babich, Cambridge, MA (US);

John Joyal, Melrose, MA (US);

Genliang Lu, Winchester, MA (US);

Kevin P. Maresca, Tewksbury, MA (US);

Chris Barone, Roxbury Crossing, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07C 311/15 (2006.01); A61K 49/00 (2006.01); A61K 31/555 (2006.01); A61K 51/04 (2006.01); A61K 31/444 (2006.01); A61K 31/4192 (2006.01); A61K 31/18 (2006.01);
U.S. Cl.
CPC ...
A61K 51/0406 (2013.01); A61K 51/0459 (2013.01); A61K 51/0455 (2013.01); A61K 31/555 (2013.01); A61K 51/0453 (2013.01); A61K 31/444 (2013.01); A61K 51/0474 (2013.01); A61K 51/0446 (2013.01); A61K 31/4192 (2013.01); A61K 31/18 (2013.01);
Abstract

Novel radiopharmaceuticals that are useful in diagnostic imaging and therapeutic treatment of disease characterized by over expression of CA-IX comprise a complex that contains a sulfonamide moiety which is capable of binding the active catalytic site of CA-IX, and a radionuclide adapted for radioimaging and/or radiotherapy:


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