The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Sep. 10, 2008
Applicants:

Zhiwei Jiang, Stow, MA (US);

Chiang Jia LI, Cambridge, MA (US);

Wei LI, Wayland, MA (US);

David Leggett, Milton, MA (US);

Inventors:

Zhiwei Jiang, Stow, MA (US);

Chiang Jia Li, Cambridge, MA (US);

Wei Li, Wayland, MA (US);

David Leggett, Milton, MA (US);

Assignee:

Boston Biomedical, Inc., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/343 (2006.01); C07D 307/92 (2006.01); A61K 31/38 (2006.01);
U.S. Cl.
CPC ...
C07D 307/92 (2013.01); A61K 31/38 (2013.01);
Abstract

The present invention relates to a novel naphtho class of compounds as Stat3 pathway inhibitors and as cancer stem cell inhibitors; to methods of using such compounds to treat cancer; to methods of using such compounds to treat disorders in a mammal related to aberrant Stat3 pathway activity; to pharmaceutical compositions containing such compounds.


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