The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Aug. 06, 2007
Applicants:
Lewis Cantley, Cambridge, MA (US);
Matthew G. Vander Heiden, Somerville, MA (US);
Heather R. Christofk, Carlsbad, CA (US);
Inventors:
Lewis Cantley, Cambridge, MA (US);
Matthew G. Vander Heiden, Somerville, MA (US);
Heather R. Christofk, Carlsbad, CA (US);
Assignee:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01); A61K 31/381 (2006.01); A61K 31/4184 (2006.01); A61K 31/402 (2006.01); A61K 31/426 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61K 31/00 (2013.01); A61K 31/381 (2013.01); A61K 31/402 (2013.01); A61K 31/426 (2013.01);
Abstract
The invention provides pharmaceutical compositions, kits, and methods of treating cancer, diabetes, obesity, autoimmune disease, and benign prostatic hyperplasia using compounds that selectively inhibit pyruvate kinase M2 and an assay measuring chemical modulation of pyruvate kinase activity.