The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Dec. 02, 2013
Applicants:
Yuki Iwaki, Tokyo, JP;
Toshio Kawanami, Boston, MA (US);
Gary Michael Ksander, Amherst, NH (US);
Muneto Moji, Waltham, MA (US);
Inventors:
Yuki Iwaki, Tokyo, JP;
Toshio Kawanami, Boston, MA (US);
Gary Michael Ksander, Amherst, NH (US);
Muneto Moji, Waltham, MA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/41 (2006.01); A61K 31/42 (2006.01); C07D 257/06 (2006.01); C07D 261/14 (2006.01); C07D 231/40 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/41 (2013.01); C07D 261/14 (2013.01); C07D 231/40 (2013.01); A61K 31/42 (2013.01); A61K 45/00 (2013.01); C07D 257/06 (2013.01);
Abstract
The present invention provides a compound of formula I; or a pharmaceutically acceptable salt thereof, wherein R, R, R, R, R, A, A, X, s and m are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.