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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8877757 B1

PDFFull Text
Date of Patent:
Nov. 04, 2014

Filed:

Aug. 31, 2011

Pyrazine derivatives and use as pi3k inhibitors

Applicants:

Pascale Gaillard, Collonges sous Salève, FR;

Anna Quattropani, Geneva, CH;

Vincent Pomel, Groisy, FR;

Thomas Rueckle, Geneva, CH;

Jasna Klicic, Biberach, DE;

Dennis Church, Commugny, CH;

Inventors:

Pascale Gaillard, Collonges sous Salève, FR;

Anna Quattropani, Geneva, CH;

Vincent Pomel, Groisy, FR;

Thomas Rueckle, Geneva, CH;

Jasna Klicic, Biberach, DE;

Dennis Church, Commugny, CH;

Assignee:

Merck Serono SA, Coinsins, Vaud, CH;

Attorney:

Saliwanchik, Lloyd & Eisenschenk

Primary Examiner:

Jeffrey H Murray

Int. Cl.
CPC ...
A01N 43/58 (2006.01); A01N 43/60 (2006.01); A61K 31/50 (2006.01); A61K 31/495 (2006.01); C07D 471/00 (2006.01); C07D 403/12 (2006.01); C07D 405/12 (2006.01); C07D 241/44 (2006.01); C07D 471/04 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01); C07D 401/12 (2006.01); C07D 417/12 (2006.01); C07D 413/12 (2006.01);
U.S. Cl.
CPC ...
C07D 241/44 (2013.01); C07D 403/12 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 407/12 (2013.01); C07D 409/12 (2013.01); C07D 401/12 (2013.01); C07D 417/12 (2013.01); C07D 413/12 (2013.01);
Abstract

The present invention is related to pyrazine derivatives of Formula (I) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.

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