The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Oct. 06, 2010
Applicants:

T. G. Murali Dhar, Newtown, PA (US);

John V. Duncia, Newtown, PA (US);

Daniel S. Gardner, Furlong, PA (US);

Weiwei Guo, Ewing, NJ (US);

John Hynes, Washington Crossing, PA (US);

Inventors:

T. G. Murali Dhar, Newtown, PA (US);

John V. Duncia, Newtown, PA (US);

Daniel S. Gardner, Furlong, PA (US);

Weiwei Guo, Ewing, NJ (US);

John Hynes, Washington Crossing, PA (US);

Assignee:

Bristol-Myers Squibbs Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); C07D 413/12 (2006.01); C07D 471/04 (2006.01); C07D 405/12 (2006.01); A61K 31/4427 (2006.01); C07D 401/12 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 471/04 (2013.01); C07D 405/12 (2013.01); A61K 31/4427 (2013.01); C07D 413/12 (2013.01);
Abstract

The present application describes modulators of chemokine receptor activity of formula (I) or stereoisomers or pharmaceutically acceptable salts thereof. In addition, methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using modulators of formula (I) are disclosed.


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