The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Apr. 13, 2012
Applicants:
Aesop Cho, Mountain View, CA (US);
Choung U. Kim, San Carlos, CA (US);
Thorsten A. Kirschberg, Redwood City, CA (US);
Michael R. Mish, Foster City, CA (US);
Neil Squires, San Francisco, CA (US);
Inventors:
Aesop Cho, Mountain View, CA (US);
Choung U. Kim, San Carlos, CA (US);
Thorsten A. Kirschberg, Redwood City, CA (US);
Michael R. Mish, Foster City, CA (US);
Neil Squires, San Francisco, CA (US);
Assignee:
Gilead Sciences, Inc., Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/70 (2006.01); C07H 19/06 (2006.01); A61K 31/196 (2006.01); C07H 19/073 (2006.01); A61K 31/7068 (2006.01); C07H 19/067 (2006.01); A61K 31/7072 (2006.01); C07H 19/09 (2006.01); C07H 19/10 (2006.01); A61K 45/06 (2006.01); A61K 31/351 (2006.01); A61K 31/245 (2006.01); C07H 19/11 (2006.01); A61K 38/21 (2006.01); A61K 31/13 (2006.01);
U.S. Cl.
CPC ...
C07H 19/06 (2013.01); A61K 31/196 (2013.01); C07H 19/073 (2013.01); A61K 31/7068 (2013.01); C07H 19/067 (2013.01); A61K 31/7072 (2013.01); C07H 19/09 (2013.01); C07H 19/10 (2013.01); A61K 45/06 (2013.01); A61K 31/351 (2013.01); A61K 31/245 (2013.01); C07H 19/11 (2013.01); A61K 38/21 (2013.01); A61K 31/13 (2013.01);
Abstract
Provided are compounds of Formula I: nucleosides, nucleoside phosphates and prodrugs thereof, wherein Ris CN, ethenyl, 2-haloethen-1-yl, or (C-C)-alkyn-1-yl. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections.