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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8877732 B1

PDFFull Text
Expired
Date of Patent:
Nov. 04, 2014

Filed:

Jan. 11, 2011

Combination, kit and method of reducing intraocular pressure

Applicants:

Norman N. Kim, Westford, MA (US);

William K. Mcvicar, Sudbury, MA (US);

Thomas G. Mccauley, Cambridge, MA (US);

Rudolf A. Baumgartner, Sudbury, MA (US);

Inventors:

Norman N. Kim, Westford, MA (US);

William K. McVicar, Sudbury, MA (US);

Thomas G. McCauley, Cambridge, MA (US);

Rudolf A. Baumgartner, Sudbury, MA (US);

Assignee:

Inotek Pharmaceuticals Corporation, Lexington, MA (US);

Attorneys:

Nelson Mullins Riley & Scarborough LLP

Jane E. Remillard, Esq.

Cynthia L. Kanik

Primary Examiner:

Lawrence E Crane

Int. Cl.
CPC ...
A61K 31/70 (2006.01); A61K 31/24 (2006.01); A61K 31/215 (2006.01); A61K 31/235 (2006.01); A01N 43/04 (2006.01); A01N 37/08 (2006.01); A01N 37/10 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 31/7076 (2006.01); A61K 31/19 (2006.01); A61K 31/165 (2006.01); A61K 31/216 (2006.01); A01N 37/12 (2006.01); A01N 37/44 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 9/0048 (2013.01); A61K 31/7076 (2013.01); A61K 31/19 (2013.01); A61K 31/165 (2013.01); A61K 31/216 (2013.01);
Abstract

The present invention is directed to a combination or a kit comprising a prostaglandin analog and an adenosine receptor Aagonist and to a method of reducing intraocular pressure (IOP) in a subject using such combination or kit. In one embodiment, the prostaglandin analog is latanoprost and the adenosine receptor Aagonist is Compound A, ((2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl nitrate, having the structure,

Find Patent Forward Citations

Kim, Norman. (2014). Combination, kit and method of reducing intraocular pressure (U.S. Patent No. 8877732). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8877732

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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