The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Oct. 28, 2009
Applicants:
Charlotte Admyre, Stockholm, SE;
Lars-göran Axelsson, Tierp, SE;
Oliver Von Stein, Upplands Väsby, SE;
Arezou Zargari, Solna, SE;
Inventors:
Charlotte Admyre, Stockholm, SE;
Lars-Göran Axelsson, Tierp, SE;
Oliver Von Stein, Upplands Väsby, SE;
Arezou Zargari, Solna, SE;
Assignee:
Index Pharmaceuticals AB, Stockholm, SE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); A61K 31/7125 (2006.01); C12N 15/117 (2010.01); A61K 31/7088 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 31/7088 (2013.01); C12N 2310/17 (2013.01); A61K 31/7125 (2013.01); C12N 15/117 (2013.01); C12N 15/1138 (2013.01);
Abstract
A therapeutically effective amount of an oligonucleotide is capable of influencing the properties and behavior of polymorphonuclear cells, e.g. suppressing endothelial adhesion and transmigration of said cells, and through this mechanism reduce the recruitment and/or migration of polymorphonuclear cells to a site of inflammation.