The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Mar. 15, 2013
Applicant:
Bio-thera Solutions, Ltd., Co., Guangzhou, CN;
Inventors:
Shenfeng Li, Belmont, CA (US);
Xiaobin Deng, Guangzhou, CN;
Songnuan Tan, Guangzhou, CN;
Weijia Tang, Guangzhou, CN;
Chao Qin, Guangzhou, CN;
Assignee:
Bio-Thera Solutions Ltd., Co., Guangzhou Science, CN;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); C07D 498/08 (2006.01); C07K 16/30 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07D 498/08 (2013.01); C07K 16/30 (2013.01); A61K 47/48569 (2013.01);
Abstract
Disclosed herein are maytansinoid drug linker derivatives which can be linked to a antigen binding unit (Abu), and maytansinoid drugs linked with an antigen binding unit (Drug-Linker-Antigen binding Unit: D-L-Abu), for targeted delivery to disease tissues. D-L-Abu, D-L-Abu derivatives, and methods relating to the use of such drug conjugates to treat antigen positive cells in cancers and immunological disorders are provided.