The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Jun. 17, 2013
Applicant:

Universite Libre DE Bruxelles, Brussels, BE;

Inventors:

Philippe Gabant, Ottignies-Louvain-la-Nueve, BE;

Laurence Van Melderen, Waterloo, BE;

Cedric Yves Szpirer, Fleurus, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/70 (2006.01); C07K 14/245 (2006.01); C12N 15/10 (2006.01); C12N 15/65 (2006.01); C12N 15/66 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C12N 15/70 (2013.01); C07K 14/245 (2013.01); C12N 15/10 (2013.01); C12N 15/65 (2013.01); C12N 15/66 (2013.01); C12N 15/1034 (2013.01);
Abstract

The present invention is related to a method for the selection of recombinant clones having integrated a gene of interest and a nucleotide sequence encoding a functional antidote protein to a toxic molecule, wherein said recombinant clones are the ones which survive following their integration into a host cell comprising in its genome a nucleotide sequence encoding said toxic molecule. The present invention is also related to a nucleic acid construct, a vector comprising said nucleic acid construct, a host cell and a cloning and/or sequencing kit for performing said method.


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