The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2014
Filed:
Dec. 04, 2009
Kenji Yasuda, Bunkyo-ku, JP;
Atsushi Sugiyama, Bunkyo-ku, JP;
Tomoyuki Kaneko, Bunkyo-ku, JP;
Fumimasa Nomura, Bunkyo-ku, JP;
Kenji Yasuda, Bunkyo-ku, JP;
Atsushi Sugiyama, Bunkyo-ku, JP;
Tomoyuki Kaneko, Bunkyo-ku, JP;
Fumimasa Nomura, Bunkyo-ku, JP;
Abstract
Provided is a device and a method for examining myocardial toxicity, which can be realized in vitro in an equivalent manner as those conventionally carried out in vivo. A cell population as a pulsating pacemaker is arranged on a transparent substrate. Myocardial pulsating cells are arranged while being spaced apart appropriately. Fibroblast cells are arranged with/connected to the myocardial pulsating cells to form a cell network. Each of the myocardial pulsating cells and fibroblast cells forming the network is arranged on a transparent electrode provided on the transparent substrate. The cells forming the network are exposed to a flow of a solution containing a drug and QT delay due to the drug is evaluated.