The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Jul. 18, 2011
Applicants:

Annamaria Cimini, L'Aquila, IT;

Barbara D'angelo, L'Aquila, IT;

Soumen Das, Orlando, FL (US);

Sudipta Seal, Orlando, FL (US);

Inventors:

Annamaria Cimini, L'Aquila, IT;

Barbara D'Angelo, L'Aquila, IT;

Soumen Das, Orlando, FL (US);

Sudipta Seal, Orlando, FL (US);

Assignees:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01); A61K 39/385 (2006.01); A61K 38/00 (2006.01); A61K 47/48 (2006.01); B82Y 5/00 (2011.01);
U.S. Cl.
CPC ...
A61K 47/48907 (2013.01); A61K 47/48538 (2013.01); A61K 47/48861 (2013.01); B82Y 5/00 (2013.01);
Abstract

Disclosed is a composition immunologically targeted to Alzheimer's disease (AD), the composition containing amine functionalized nanoparticles of Cerium oxide coated with polyethylene glycol and bearing an antibody specific for an amyloid-beta antigen associated with AD. The invention also includes a medication manufactured with the targeted nanoceria particles and methods of treatment by administering the targeted nanoceria particles to patients in need thereof.


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