The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2014

Filed:

Jan. 31, 2011
Applicants:

Kai Licha, Falkensee, DE;

Michael Schirner, Berlin, DE;

Pia Welker, Berlin, DE;

Rainer Haag, Berlin, DE;

Marie Weinhart, Berlin, DE;

Florian Paulus, Berlin, DE;

Inventors:

Kai Licha, Falkensee, DE;

Michael Schirner, Berlin, DE;

Pia Welker, Berlin, DE;

Rainer Haag, Berlin, DE;

Marie Weinhart, Berlin, DE;

Florian Paulus, Berlin, DE;

Assignee:

Mivenion GmbH, Berlin, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/74 (2006.01); C08G 83/00 (2006.01); A61K 49/00 (2006.01); A61K 41/00 (2006.01); C07D 487/22 (2006.01); A61K 49/08 (2006.01); C07C 237/14 (2006.01); C07D 403/14 (2006.01); C07D 403/10 (2006.01); C07D 405/12 (2006.01); A61K 47/48 (2006.01); A61K 49/12 (2006.01); C07H 21/02 (2006.01); A61K 51/06 (2006.01);
U.S. Cl.
CPC ...
C07D 487/22 (2013.01); C08G 83/003 (2013.01); A61K 49/0041 (2013.01); A61K 41/0071 (2013.01); A61K 49/085 (2013.01); A61K 49/0032 (2013.01); C07C 237/14 (2013.01); C07D 403/14 (2013.01); C07D 403/10 (2013.01); C07D 405/12 (2013.01); A61K 47/48192 (2013.01); A61K 49/124 (2013.01); C07H 21/02 (2013.01); A61K 51/065 (2013.01); A61K 49/0054 (2013.01);
Abstract

The present invention relates generally to methods and compositions for targeting of intracellular molecules involved in proliferation and protein synthesis of activated cells using polyanionic multivalent macromolecules. In particular aspect, multiple sulfate groups linked to polyol are specifically targeted to the cytoplasm and nucleus of proliferating and activated cells. The invention further comprises novel polyanionic macromolecular compounds and formulations.


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