The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2014

Filed:

Mar. 30, 2011
Applicants:

Fréderic Bailly, Paris, FR;

Thomas Priem, Paris, FR;

Philippe Vayron, Paris, FR;

Inventors:

Fréderic Bailly, Paris, FR;

Thomas Priem, Paris, FR;

Philippe Vayron, Paris, FR;

Assignee:

Sanofi, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 307/00 (2006.01); C07D 307/81 (2006.01); C07D 307/80 (2006.01); C07D 307/79 (2006.01);
U.S. Cl.
CPC ...
C07D 307/81 (2013.01); C07D 307/80 (2013.01); C07D 307/79 (2013.01);
Abstract

The invention relates to a method for preparing 3-keto-benzofurane derivatives of the general formula: Formula (I), where R is an alkyl or aryl group, Ris hydrogen or an alkyl or aryl group, and Ris a substituted alkyl or phenyl group. Said preparation method involves coupling a derivative of Formula III, where X is chlorine, bromine, or iodine or a sulfonate grouping: Formula (III) with a sulfonamide derivative of the formula R—SO—NHin the presence of a basic agent and a catalytic system formed of a complex between a palladium compound and a ligand.


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