The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2014

Filed:

Jan. 11, 2013
Applicant:

New York University School of Medicine, New York, NY (US);

Inventor:

Chuanju Liu, Orange, CT (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/475 (2006.01); A61K 38/18 (2006.01); A61P 29/00 (2006.01); A61K 45/06 (2006.01); A61K 49/00 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/18 (2013.01); A61K 45/06 (2013.01); C07K 14/475 (2013.01); A61K 38/00 (2013.01); C07K 2319/00 (2013.01); G01N 2333/525 (2013.01); A61K 49/0008 (2013.01); G01N 33/5008 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention provides modulators of TNF, particularly peptides and their derivatives, particularly GEP peptides, which antagonize TNF and TNF-mediated responses, activity or signaling. The invention provides methods of antagonizing TNF and the modulation of TNF-mediated diseases or responses, including inflammatory diseases and conditions. Compositions of GEP peptides, including in combination with other inflammatory mediators, are provided. Methods of treatment, alleviation, or prevention of TNF-mediated diseases and inflammatory conditions, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, inflammatory bowel diseases, Chrohn's disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, are provided.


Find Patent Forward Citations

Liu, Chuanju. (2014). Peptides targeting tnf family receptors and antagonizing tnf action, compositions, methods and uses thereof (U.S. Patent No. 8871915). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8871915

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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