The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 28, 2014
Filed:
Oct. 16, 2012
Applicant:
Sanofi, Paris, FR;
Inventors:
Karl Schoenafinger, Alzenau, DE;
Henning Steinhagen, Schwalbach am Taunus, DE;
Bodo Scheiper, Munich, DE;
Uwe Heinelt, Wiesbaden, DE;
Volkmar Herrmann, Sandberg, DE;
Matthias Herrmann, Hofheim, DE;
Assignee:
Sanofi, Paris, FR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/14 (2006.01); C07D 487/14 (2006.01); C07D 498/14 (2006.01); A61K 31/407 (2006.01); A61K 31/437 (2006.01); A61K 31/4985 (2006.01); A61K 31/5383 (2006.01); A61P 7/02 (2006.01);
U.S. Cl.
CPC ...
C07D 471/14 (2013.01); C07D 487/14 (2013.01); C07D 498/14 (2013.01);
Abstract
This disclosure relates to compounds of formula I: wherein R1, R2, R3, R4, X and Y have the meanings denoted in the disclosure. The compounds of formula I have antithrombotic activity and in particular inhibit the protease-activated receptor 1 (PAR1). The disclosure further relates to a method for producing the compound of formula I and to the use thereof as a pharmaceutical product.